How to Beat Skeletron Prime in Terraria
Pro tip: Focus on dodging first; Skeletron Prime's attacks can be brutal. Use weapons that have good range or can attack through walls, like the Daedalus Stormbow with Holy Arrows. Buff potions are your best friend - Ironskin, Regeneration, and Swiftness will help a lot. Make sure you have a solid arena with platforms to move around easily. Lastly, don't forget to summon the Mechanical Skull at night, or Skeletron Prime will disappear by morning!
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Honestly, Skeletron Prime isn't even that hard. Just make sure your gear is up to date and hit it till it dies. People overcomplicate it.
Just use the Megashark with Crystal Bullets and build a big arena with platforms and heart lanterns around. Easy peasy.
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