How to Break The Binding of Isaac: Afterbirth?

avatarHatchellingCalm3 months ago
Best Answer
avatarBakingAlert3 months ago

Try combining the Blank Card with the Jera rune or the 2 of Diamonds card. You'll be rolling in resources faster than you can say 'Isaac!'

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More Answers

avatarDistributingJoke3 months ago

One of my favorite ways to break the game is using the D20 on a room with lots of pickups to reroll for potentially game-breaking items. All those pennies and keys become a goldmine!


avatarInterferingHood3 months ago

Use the combination of the Smelter and trinkets like Cancer or Curved Horn. Stack those bonuses and watch Isaac become unstoppable!


avatarArisingWard3 months ago

Get the IV Bag or the Blood Donation Machine, combine it with the Piggy Bank and the D20, and watch the magic happen.


avatarAutocancellingWeek3 months ago

D20 + battery-fueled infinite poop spawns. It's gross but effective!

馃憖 If you like The Binding of Isaac...

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