How to loop in The Binding of Isaac
To loop in The Binding of Isaac, you need to defeat Mega Satan or Delirium. That unlocks the Void floor, which lets you start a new run with your current items and stats!
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I've done it by beating Mom's Heart and getting taken down to Sheol or the Cathedral. Keep an eye out for special doors after the battle!
You can achieve a loop by defeating the final boss and choosing not to ascend, allowing you to go back to an earlier floor to replay.
Just defeat Mom鈥檚 Heart 11 times. Seriously, that unlocks the It Lives fight, which is key to looping.
馃憖 If you like The Binding of Isaac...
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