How to Progress Through The Binding of Isaac

Best Answer

Explore every room! You never know where you'll find powerful upgrades or hidden items that'll make your run so much easier.

Win gift cards by playing fun games on Playbite!

Playbite

(13.7k)

500k winners and counting...

More Answers

ConcludingDisc·3 months ago

Focus on upgrading your stats with items you find and always check for secret rooms. Bombs are your best friend here!

NailingSurge·3 months ago

Make sure to use your bombs to find secret rooms—they often contain game-changing items or extra health.

AttemptingDance·3 months ago

Mastering Isaac is all about learning enemy patterns and managing your resources well. Practice makes perfect, so keep playing!

👀 If you like The Binding of Isaac...

Diego·3 hours ago

...you need to download the Playbite app!

Playbite is like an arcade in your phone: you get to play all kinds of fun and simple games, compete with friends and others, and win cool prizes from all your favorite brands!

This includes gift cards from all your favorite brands, like Amazon, Starbucks, Apple, Roblox, and many, many more!

In case you're wondering, this is how it works:

Playbite makes money from (not super annoying ads) and (totally optional) in-app purchases. The app then uses that money to reward players like you with prizes!

Download Playbite for free, available on the App Store and Play Store!

The brands referenced on this page are not sponsors of the rewards or otherwise affiliated with this company. The logos and other identifying marks attached are trademarks of and owned by each represented company and/or its affiliates. Please visit each company's website for additional terms and conditions.

People also want to know

How many bosses are in The Binding of Isaac: Rebirth?

How to Play Co-op in The Binding of Isaac: Repentance?

Is The Binding of Isaac Multiplayer on PC?

How to unlock the scythes in The Binding of Isaac

How to take off trinkets in The Binding of Isaac

Add an Answer