How to Swap Items in The Binding of Isaac
You can drop trinkets and pills/cards by holding the 'Drop' button (usually the L2/LT key on consoles or the left CTRL on PC). But for regular items, once you pick them up, you can't swap them out.
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Hot take: Just embrace the chaos! The randomness is what makes The Binding of Isaac so much fun.
Unfortunately, you can't directly swap items once you've picked them up in The Binding of Isaac, so choose wisely when deciding which ones to take!
From personal experience, it's all about strategy and knowing what items to prioritize. Understand item synergies and choose carefully for the best runs!
馃憖 If you like The Binding of Isaac...
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