What is the Best Item in The Binding of Isaac?
Brimstone, no contest! Who wouldn't want to transform into a laser-firing nightmare?
Win gift cards by playing fun games on Playbite!
Playbite
(13.7k)
500k winners and counting...
More Answers
Tech X. Circles of death that can clear rooms faster than I can say 'Isaac'? Sign me up!
Sacred Heart is just chef's kiss for those massive damage, homing tears. Divine intervention done right!
Honestly, it's Holy Mantle. That extra hit you can take every room is a literal lifesaver!
Polyphemus for that sweet damage boost! Insta-melting enemies never gets old.
馃憖 If you like The Binding of Isaac...
Diego路3 hours agoThe brands referenced on this page are not sponsors of the rewards or otherwise affiliated with this company. The logos and other identifying marks attached are trademarks of and owned by each represented company and/or its affiliates. Please visit each company's website for additional terms and conditions.
People also want to know
Add an Answer