What is the Hardest Boss in The Binding of Isaac

avatarReoccuringRace3 months ago
Best Answer
avatarRemovingMyth3 months ago

Hush has to be the hardest for me. Endless bullet hell and tanky as a brick wall. Bring lots of damage or good luck!

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avatarCopyingSole3 months ago

Delirium. Period. That boss morphs into every other boss, keeps you on your toes with unpredictable movements. Pure chaos!


avatarBakingAlert3 months ago

Ultra Greed can really ruin your day鈥攈e's got so much health and those phases are just brutal!


avatarCarryingMonte3 months ago

Honestly, The Beast isn't too tough once you get the hang of it. Try focusing on pattern recognition鈥攊t helps a lot!


avatarCoilingShip3 months ago

Believe it or not, I think Mega Satan is overrated in difficulty. As long as you have good crowd control, he's manageable.

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