Who is the Main Villain in Naruto Shippuden?
The main villain in Naruto Shippuden is Madara Uchiha. He's the big bad with crazy ninja skills and a god complex.
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Madara Uchiha. No contest.
While Madara Uchiha is the main antagonist for much of the series, don't forget Kaguya Otsutsuki who also plays a significant role in the end.
It's complicated. Madara Uchiha is a key villain, but Kaguya Otsutsuki and even Obito Uchiha have their moments too.
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